ODCs

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3 associated genes
7 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
No signs/symptoms info

Mantle cell lymphoma

Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ATM	(0.75)	BRCA2

Citations in the biomedical literature:

Mantle cell lymphoma		Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
	Synonym(s): - LCM - MCL - Mantle zone lymphoma		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare oncologic disease - Rare renal disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: adult Type of inheritance: multigenic/multifactorial		Epidemiological data: (no data available)

	External references: No OMIM references 1 MeSH reference: D020522		External references: 1 OMIM reference - No MeSH references

Mantle cell lymphoma
	Very frequent - Hematologic / blood / lymphatic cancer - Lymphadenopathy / polyadenopathies Frequent - Anorexia - Asthenia / fatigue / weakness - Bone marrow / medullar infiltration - Splenomegaly - Weight loss / loss of appetite / break in weight curve / general health alteration
Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
(no data available)